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International Journal of Latest Research in Science and Technology

DOI:10.29111/ijlrst   ISRA Impact Factor:3.35,  Peer-reviewed, Open-access Journal

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IN - VITRO ANTIMICROBIAL ACTIVITY OF FRAMYCETIN AND PARAFFIN WOUNDDRESSING TO METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) ANDPSEUDOMONAS AERUGINOSA

Research Paper Open Access

International Journal of Latest Research in Science and Technology Vol.5 Issue 2, pp 98-101,Year 2016

IN - VITRO ANTIMICROBIAL ACTIVITY OF FRAMYCETIN AND PARAFFIN WOUNDDRESSING TO METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) ANDPSEUDOMONAS AERUGINOSA

Yeva Rosana, Vanya Utami Tedhy, Indah Lestari

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Received : 23 April 2016; Accepted : 28 April 2016 ; Published : 30 April 2016

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Article No. 10647
Abstract

A good dressing provides good barrier against bacterial infection to promote natural wound healing. Framycetin and paraffin wound dressings have long been used to cover wounds to prevent infection. This study aims to determine in-vitro antimicrobial activity of framycetin and paraffin wound dressing to Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, multidrug resistant bacteria which are frequently found on superficial wound infection. In vitro study was conducted by exposing suspension of MRSA and Pseudomonas aeruginosa to framycetin and paraffin wound dressing. The suspension was diluted in ten time serial dilution. Plating on agar plates was done at exposure time of 0, ½, 2, 4, 6, and 24 hours. Antimicrobial activity of dressing is defined as its ability to inhibit bacterial growth. The result showed that framycetin wound dressing had antimicrobial activity against MRSA at ½ to 24 hours exposure time with bactericidal effect at 4, 6, and 24 hours. Its antimicrobial activity against Pseudomonas aeruginosa was shown at 4, 6, and 24 hours. Paraffin wound dressing showed antimicrobial activity to both bacteria at 4 and 24 hours with addition of 6 hours for MRSA. Antimicrobial activity of framycetin wound dressing against MRSA and Pseudomonas aeruginosa were superior to paraffin wound dressing.

Key Words   
Antimicrobial activity, Framycetin wound dressing, Methicillin-resistant Staphylococcus aure

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To cite this article

Yeva Rosana, Vanya Utami Tedhy, Indah Lestari , " In - Vitro Antimicrobial Activity Of Framycetin And Paraffin Wounddressing To Methicillin-resistant Staphylococcus Aureus (mrsa) Andpseudomonas Aeruginosa ", International Journal of Latest Research in Science and Technology . Vol. 5, Issue 2, pp 98-101 , 2016

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